By using US/South Korea/China-patented DNA microarray technology, GoodGene has developed a DNA microarray, GG Human Papilloma Virus DNA chip, which can detect clinically important human papillomaviruses in entirety, used and validated in many countries, and which has been one of the first HPV DNA chips ever developed around the world.

Although commonly used, PCR/Sequencing is labor-intensive and impractical for high throughput screening of respiratory diseases required in clinical laboratories. The FDA-approved real-time PCR tests are effective for qualitative detection, but notable for two major limitations 1) constrained spectrum of bacterias/viruses detected, and 2) non-specific dichotomous results. These limitations, therefore, urge the development of a comprehensive, sensitive, specific, automated test that has broad clinical applications from epidemiological surveillance to vaccine development.

The DNA chips can analyze the more than 40 types of HPV found in the cervical, diagnose complex infection by at least one type of HPV, and have excellent diagnostic sensitivity and specificity on HPV genetic type up to 100% and reproducibility. Also, the DAN chips are superior to the conventional analytic methods, and very economical, since they can analyze numerous specimens in shortest time. Accordingly, DNA chips are useful for predicting cervical cancer and precancerous lesions.

It is a semi-automated essay and takes around 4 hours for two or three laboratory scientists to test hundreds of samples. The novel array in comparison to direct DNA sequencing offers the greatest specificity and breadth of detection for known single and mixed infections. To extend the use of this DNA chip, we are searching for laboratories to collaborate for the widespread use of microarray technology for HPV genotyping.

To get a quote for this DNA microarray: